Knowledge Base

Learn more about the power of trace gas analysis using SIFT-MS. Download our latest brochures, application notes and white papers or watch an application-focused video. Questions? Contact us!

In this presentation from the 2019 North American User's Meeting, Dr. Mitch Rubenstein and Anthony Qualley describe their ground-breaking passive dosimetry research and how automated SIFT-MS advanced their workflow.  

Kurt Thaxton, the International Product Manager for Pyrolysis and Thermal Desorption products at GERSTEL, provides a fast-paced overview of the whys and hows of integration of thermal desorption (TD) with SIFT-MS in this presentation from the 2019 SIFT-MS North American user's meeting. 

This Syft Tech Talk provides the foundational knowledge of SIFT-MS ion-molecule reaction trends. Applying this knowledge to the practical interpretation of SIFT-MS data will bring improved confidence in SIFT-MS compound identification and greater success when identifying product ions for compound addition to the SIFT-MS library.

What really differentiates SIFT-MS from other direct mass spectrometry techniques is the unique combination of ions generated conveniently from moist or dry air coupled with the ultra-soft chemical ionization (USCI) approach applied in the SIFT-MS instrument’s flow tube.  This Syft Tech Talk describes how these attributes enable sensitive and selective analysis of the widest range of volatiles.

In this presentation, Dr. Vaughan Langford describes the principles by which questions about what can by analyzed by SIFT-MS can be answered and gives an outline of how we begin to develop a new application.

This presentation, recorded at the 2020 European Online SIFT-MS User Meeting, describes the development of an automated method for the determination of a range of chlorinated and aromatic hydrocarbon compounds in water. It also describes how Syft’s dual-polarity ion source can be utilized for efficient headspace analysis when chloroform and dichloromethane need to be resolved.

IFA provides proficiency testing schemes for various hazardous substances (VOCs, aldehydes and inorganic acids) at its dynamic test gas facility. By using SIFT-MS, the quantitative real-time analysis of all currently used substances in IFAs test gas facility is possible. Furthermore, SIFT-MS is successfully applied in the development of a new dosing system.

This presentation demonstrates validation of a method for the determination of a range of chlorinated and aromatic hydrocarbon compounds in water. By following the methodology detailed in the ICH 2Q guidelines on method validation, originally developed for GC/MS analysis, these guidelines can be equally applied to automated SIFT-MS methods.

A system to differentiate and quantify liquid and headspace leaks from closed system transfer devices (CSTDs) is presented by Dr. Amos Doepke.  Dr. Doepke is a chemist and Senior Service Fellow at the National Institute for Occupational Safety and Health (NIOSH).

Kurt Thaxton, GERSTEL, discusses several ways that GERSTEL has worked with Syft to solve the problem of getting sample to the SIFT-MS when sampling directly is not possible. He describes a fully automated process for obtaining easy and rapid answers.

This presentation describe how instrument calibration is achieved very simply and rapidly with automated SIFT-MS instrumentation.  Calibration is essential for contract testing laboratories and other regulatory measurements. Practical examples will be given to illustrate various approaches using SIFT-MS.

In this presentation, examples of real-time thermal extraction and analysis of various plastic materials using TD-SIFT-MS are demonstrated, and its application to product development and processing environments are discussed. Direct, continuous analysis of formaldehyde from polyoxymethylene (POM) is of particular significance.