Knowledge Base
Learn more about the power of trace gas analysis using SIFT-MS. Download our latest brochures, application notes and white papers or watch an application-focused video. Questions? Contact us!
Rapid Untargeted Screening of Food and Ingredient Aroma Using SIFT-MS
This application note surveys the application of headspace-SIFT-MS to untargeted screening of food products and ingredients, such as beer, olive oil, Parmesan cheese, and strawberry flavor mixes. Rapid quality assurance (QA) and quality control (QC) screening of up to 250 samples/day can be conducted using an untargeted approach.
High-Throughput Analysis of Polymers for Benzene and Volatile MOSH and MOAH Residues
This application note describes the utility of SIFT-MS in pre-screening polymer packaging materials for volatile MOSH and MOAH compounds. Automated SIFT-MS can characterize 12 high-density polyethylene (HDPE) and polypropylene (PP) samples per hour, or 220 / day. Headspace-SIFT-MS readily analyzes benzene at high sensitivity as part of the same analysis.
Real-Time Monitoring of Volatile Organic Compounds in Ambient Air Using Direct Injection Mass Spectrometry
In this article, the results of a DIMS air monitoring campaign in Auckland, New Zealand, are described. Real-time SIFT–MS measurements were obtained at three sites over a period of several weeks each. At each site, SIFT–MS provided effective on-site analysis to sub-ppbV levels with better than 1-min time resolution.
High-Throughput Screening of Polypropylene Polymer using Untargeted Headspace-SIFT-MS Analysis
This application note describes how SIFT-MS coupled with multivariate statistical analysis can be utilized for rapid screening of pelleted virgin and recycled polypropylene using an untargeted “fingerprinting” approach. Automated headspace-SIFT-MS analysis can classify and qualify polypropylene samples at throughputs of over 230 samples per day, offering great potential for rapid screening of recycled polypropylene feedstock for FCM applications. Adoption of SIFT-MS supports product quality and enhances sustainability.
Real-Time Analysis of Volatile Emissions from Hot-Melt Extrusion using Untargeted SIFT-MS
SIFT-MS provides unique capabilities that enable formulators to optimize the hot melt extrusion processes by minimizing polymer, API, and other excipient degradation. SIFT-MS provides real-time feedback though online, ultra-trace, gas-phase analysis of the small molecules emitted when the mixture is extruded, benefiting process development and optimization, as well as continuous process monitoring and control.
Improved MHE-SIFT-MS Workflows - Concentration Independent MHE Calibration
This application note investigates concentration dependence of MHE calibration in sample matrix. Across the full range of analytes investigated in this study, MHE calibration holds for at least one order of magnitude change in sample concentration. For analytes in the C7–C9 range, the MHE calibration applies over two orders of magnitude analyte concentration. These results mean that the MHE workflow can be applied to a wider range of samples in the matrix, further reducing calibration demand.
Fast, Simple Quantitation of Odors by SIFT-MS
In this on-demand webinar, Michael McGinley, President, St. Croix Sensory, describes how SIFT-MS has advanced their ability to rapidly perform odor analysis. A variety of SIFT-MS-based odor applications correlated with conventional sensory panel assessment are presented. Learn how Syft is Simply. Faster. for the analysis of odor compounds.
Revolutionizing Volatile Impurities Analysis Through Next Gen SIFT-MS
This E-book describes how next gen SIFT-MS enables rapid, continuous screening of toxic volatile impurities in pharmaceutical and consumer products. This advancement to SIFT-MS delivers trace-level detection sensitivity, unparalleled performance stability, superior selectivity, and highly reproducible, quantitative data. Never miss a contamination event again.
Pharmaceutical Residual Solvent Analysis: A Comparison of GC-FID and SIFT-MS Performance
This study expands upon the previous work by conducting a head-to-head comparison of GC-flame ionization detection (GC-FID) and SIFT-MS procedures. SIFT-MS analyzed samples over 11-fold faster than GC-FID, increasing daily sample throughput and reducing the time taken to determine the result. The results suggests that residual solvent analysis using SIFT-MS may support workflow improvements for pharmaceutical manufacturers.
Rapid Sensory Analysis of Paper Packaging Using SIFT-MS
This application note demonstrates that SIFT-MS effectively classifies paper samples by odor intensity rating and odor descriptor, in addition to distinguishing paper composition and mill of origin. When integrated with autosamplers, SIFT-MS provides throughputs of over 220 samples per day, supporting significantly enhanced quality assurance compared to conventional human sensory panels and gas chromatography-based analyses.
Revolutionizing Workflows for Residual Solvents and Volatile Impurities Analyses by SIFT-MS
This webinar demonstrates how the new, automated Syft TracerTM SIFT-MS platform provides a comprehensive solution to workflow challenges and can replace multiple chromatographic systems. Learn about how combining SIFT-MS with automation provides a very flexible and high throughput solution for screening volatile impurities in pharmaceutical and consumer safety applications, revolutionizing workflows.