Knowledge Base

Learn more about the power of trace gas analysis using SIFT-MS. Download our latest brochures, application notes and white papers or watch an application-focused video. Questions? Contact us!

Application Note

Syft Tracer: The Next Generation of Volatile Impurities Analysis for Enhanced Workflows

This app note introduces the next generation of SIFT-MS, Syft TracerTM, which launched at Pittcon 2023.  It revolutionizes volatile impurities analysis workflows through unparalleled speed, performance stability, and reproducibility.  Learn about how this innovation to real-time trace gas detection outpaces chromatography-based methods in the analysis of challenging analytes such as formaldehyde in a PEG excipient.

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Application Note

High-Throughput Quantitative Analysis of Residual Monomer by Using MHE-SIFT-MS to Calibrate Single Headspace Injections

MHE-SIFT-MS provides rapid, matrix-independent, quantitative determination of volatile leachables in polymers and calibrates quantitative analysis based on single headspace injections.  This approach enables over 200 samples per day to be analyzed, delivering rapid and economic analysis of volatile leachables such as residual monomers.

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Webinar

High-Throughput Analysis of Volatile Impurities in Sustainable Packaging using SIFT-MS

Pharmaceutical and food products are susceptible to contamination from packaging, whether from polymeric materials, printing inks, or paperboard.  SIFT-MS, a high-sensitivity direct-injection mass spectrometry technique, enables risks associated with sustainable packaging alternatives to be mitigated through economical, high-throughput automated analysis (typically a 4- to 15-fold increase over GC-MS).

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Webinar

Real-time Ethylene Oxide and Fence Line Monitoring Using SIFT-MS

Selected ion flow tube mass spectrometry (SIFT-MS) is a revolutionary direct mass spectrometric technology for continuous, sensitive, selective, and robust analysis of diverse chemical species in air. Volatile organic compounds (VOCs) — such as benzene, ammonia, and formaldehyde — and inorganic gases such as sulfur dioxide and hydrogen sulfide are detected simultaneously and continuously in real time.  Watch the webinar to discover why SIFT-MS is well suited to air quality monitoring both in a mobile deployment scenario and for fence line monitoring.

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Webinar

Rapid, Simplified Residual Solvent and Volatile Impurity Analysis Using SIFT-MS

SIFT-MS provides real-time, selective, and economic analysis of challenging volatile compounds, such as residual solvents, formaldehyde, dimethylamine, and NDMA without requiring derivatization or other special handling.

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Application Note

Rapid Odor Screening of Paperboard Using Static Headspace-SIFT-MS

Automated SIFT-MS analysis coupled with multivariate statistical analysis provides rapid sensory screening of paperboard packaging, overcoming the low sample throughput of sensory panels.  The ability to use HS-SIFT-MS to achieve throughput of 12 samples per hour is demonstrated.

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Application Note

Rapid, Quantitative Analysis of Volatile Aldehyde Impurities In Paperboard Using Multiple Headspace Extraction

Quantitative determination of volatile aldehyde residues in paperboard is readily achieved using multiple headspace extraction-SIFT-MS analysis, with an eight-fold throughput increase over the equivalent conventional analysis.

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Application Note

Rapid Screening of Paperboard For Volatile Leachables Using Static Headspace-SIFT-MS

Automated SIFT-MS analysis rapidly screens paperboard packaging for a wide range of functional groups in a single analysis, assuring that the volatile emissions meet manufacturer specifications.  This application note describes a Headspace-SIFT-MS method with throughput >10X faster than traditional GC/MS methods.

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Webinar

Feedback from a CDMO SIFT-MS User

Hear what Christopher Williams, Senior Manager of Analytical Development, Alcami Corporation, had to say about his experience using SIFT-MS.

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Application Note

High Throughput Screening of Recycled HDPE Pellets Using Untargeted Headspace-SIFT-MS-Analysis

Automated headspace-SIFT-MS analysis can classify pelleted recycled HDPE at throughputs over 230 samples per day, offering great potential for rapid screening of recycled packaging materials.

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Webinar

A Consumer Safety Expert Shares His Experience with SIFT-MS

We asked David Light, CEO and Founder of Valisure, about his experience using SIFT-MS and how it impacted their dry shampoo safety study.  

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Application Note

Real-Time Monitoring of Bioreactor Production Processes Using SIFT-MS

The ability of SIFT-MS to monitor critical volatile organic compounds (VOCs) produced by a bioreactor in real-time at low parts-per-billion by volume (ppbV) concentrations is demonstrated. This application note presents the results of a pilot-scale feasibility study conducted over several weeks, demonstrating the utility of SIFT-MS for maximizing production outcomes.

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