Fast Residual Solvent Analysis of Water-Insoluble Articles

3 months ago

SIFT-MS can analyze residual solvents and other volatile impurities in water-insoluble articles using a two-step process.  This application note describes a systematic evaluation of the compatibility of six organic solvents with headspace-SIFT-MS analysis following this two-step process.  Quantitative headspace analysis is achieved at 12 samples/hr, providing significant productivity improvements compared with chromatographic approaches.

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