Method Validation for Automated Headspace Analysis
Dr. Mark Perkins, Senior Applications Chemist, Anatune Limited, UK
Automated SIFT-MS enables high-throughput analytical methods to be developed quickly and easily for a wide range of analytes, measured simultaneously, using static headspace analysis.
Following on from Syft Tech Talk #7, which described the method development phase, this presentation demonstrates validation of a method for the determination of a range of chlorinated and aromatic hydrocarbon compounds in water. By following the methodology detailed in the ICH 2Q guidelines on method validation, originally developed for GC/MS analysis, these guidelines can be equally applied to automated SIFT-MS methods.
Dr Mark Perkins is a senior applications chemist and SIFT-MS expert at Anatune Limited, based in Cambridge, United Kingdom. Mark joined Anatune in early 2015. His current role supports and expands the analytical capability of SIFT-MS – with a particular focus on autosampler integration and the development of automated test methods. Prior to joining Anatune, Mark graduated from the University of Southampton, UK, with a Ph.D. in electrochemistry. Then he joined the Malaysian Rubber Board’s UK research center as a senior analyst, running the gas and liquid chromatography section – eventually becoming the head of the whole analytical section.