In this webinar, we continue our seven-episode series, which outlines the diverse applications of the SIFT-MS technique. In this fourth episode, our series presenter and expert in SIFT-MS applications, Dr Vaughan Langford, describes the wide range of biomedical and pharmaceutical applications in which SIFT-MS is employed.
SIFT-MS is a direct mass spectrometry (DMS) technique that utilizes ultra-soft chemical ionization (USCI) to provide continuous sample analysis with class-leading sensitivity (to parts-per-trillion by volume; pptV) and selectivity. It is unique among DMS techniques, as it allows rapid switching between chemical ionization agents. The excellent selectivity of SIFT-MS enables comprehensive detection of VOCs and inorganic gases, with the ability to quantify multiple analytes simultaneously. The excellent robustness to humidity and ability to analyze air or headspace samples make SIFT-MS a great solution for biomedical and pharmaceutical applications.
In the webinar, we discuss applications in these areas:
- Breath research, for which there is a significant academic literature
- Analysis of body fluid headspace
- Microbial VOC analysis
- Emerging small-molecule applications for the pharma industry