Volatile residue analysis in Drug Delivery Devices
SIFT-MS provides a very rapid and highly sensitive solution for the detection of residual monomers and other impurities in diverse drug delivery devices, including orally inhaled and nasal drug products (OINDPs), and parenteral and ophthalmic drug products (PODPs).
- Very high throughput screening via the elimination of chromatographic separation, delivering greatly reduced cost of analysis
- High selectivity and comprehensive analysis provided by eight rapidly switchable reagent ions
- High sensitivity, providing rapid warning of quality issues
- Wide linear and dynamic ranges enable one instrument to be applied readily to multiple analytical tasks
Analysis of multiple residual monomers in different polymer products.
Drug Delivery Devices benefits
Comprehensive analysis, including inorganics and chromatographically challenging compounds
Flexible sample delivery options, including automation and area sampling
Intuitive software and fast method development
High sensitivity and wide linearity range
Automated high-throughput headspace analysis
Drug Delivery Devices resources
Rapid, Simplified Residual Solvent and Volatile Impurity Analysis Using SIFT-MS
Routine Analysis 3: SIFT-MS Method Development and Validation
SIFT-MS Method Validation
Analysis of Volatile Emissions from Polymers and Paperboard
Drying Endpoint Monitoring Using SIFT-MS For Enhanced Manufacturing Of Active Pharmaceutical Ingredients
Process analysis using SIFT-MS enables the drying process to be monitored past the drying end-point measurable using conventional weighing methods. This delivers greater efficiencies for production, and lowers risk of thermally damaging sensitive APIs.
Simple, Rapid Analysis Of Ethylene Oxide In A Polysorbate 80 Excipient Using SIFT-MS
Quantitative ethylene oxide analysis in Polysorbate 80 excipient is greatly simplified using SIFT-MS, with a time to first test result that is eight-fold faster than the current compendial method and a
daily sample throughput that is 9- to 14-fold higher.
Simple, Rapid Analysis Of Formaldehyde Impurities In Gelucire Excipient Using SIFT-MS
SIFT-MS greatly simplifies formaldehyde detection and quantitation through direct, instantaneous, and sensitive (sub-ppbV) sample ionization, yielding sample throughputs of up to 250+ samples/day.