High-throughput water analysis.
Analysis of volatile compounds in water is greatly simplified by SIFT-MS. The soft chemical ionization is robust to water and enables moist samples to be analyzed directly. This contrasts with GC and GC/MS approaches, where rigorous drying needs to be undertaken after extraction or purging and trapping. Using SIFT-MS, low ppb concentrations (in water) of hydrophobic volatiles (such as BTEX and low molecular weight halocarbons) are readily detectable without drying.
Linear calibration of benzene, toluene, ethylbenzene, m-xylene, and chloroform from 2.5 to 1,000 ppb in water. Courtesy of Dr Mark Perkins, Element, UK
Water analysis benefits
Direct headspace analysis without drying
High-throughput automated analysis (>12 samples/hour)
High sensitivity and selectivity
Continuous monitoring option
Water and Soil resources
Routine Analysis 3: SIFT-MS Method Development and Validation
In this webinar, we discuss how analytical method validation is approached for SIFT-MS so that data collected can be used to support regulatory requirements. This is achieved by applying a strategic approach in accordance with ICH Q2(R1) guidelines. Finally, we will illustrate SIFT-MS method validation using two case studies: 1) common toxic volatiles in water, 2) BTEX in soil following methanolic extraction.
SIFT-MS Selected Ion Flow Tube Mass Spectrometry
Learn about direct mass spectrometry by SIFT-MS which provides real-time, quantitative analysis of volatile compounds with trace-level sensitivity. There are also no requirements of chromatography, pre-concentration, or sample prep! SIFT-MS is easy to use and interpret data.
High-Throughput Analysis of Volatiles in Air, Polymers, Water and Soil, with SIFT-MS
In this webinar, we demonstrate the advantages of using automated SIFT-MS to analyze volatiles in diverse matrices: from air samples to the headspace of polymers, soil and water samples. Formaldehyde and the BTEX compounds (benzene, toluene, ethylbenzene and the xylenes) will be utilized in various case studies. In addition, high-throughput thermal desorption-SIFT-MS and real-time thermal extraction-SIFT-MS are presented for the first time.
High-Throughput Analysis of Volatile Compounds in Air, Water and Soil Using SIFT-MS
Using the environmentally significant BTEX compounds (benzene, toluene, ethylbenzene and the xylenes) as a case study, we demonstrate high-throughput analysis from several matrices (air, water and soil). For the BTEX compounds, detection limits in the single-digit part-per-billion concentration range (by volume). We also present a calibration approach that enables speciation of ethylbenzene from the xylenes in real-time.
Rapid Analysis of BTEX in Water using Automated SIFT-MS
Selected ion flow tube mass spectrometry (SIFT-MS) combined with GERSTEL automation greatly simplifies analysis of benzene, toluene, ethylbenzene and the xylenes (BTEX) in water. This application note demonstrates the linearity, repeatability and sensitivity achievable with automated SIFT-MS. Automated static headspace (SH)-SIFT-MS provides sample throughputs at least three-fold higher than traditional purge-and-trap-gas chromatography methods.
Rapid Analysis of BTEX in Soil Using Methanolic Extraction
Combining direct analysis using selected ion flow tube mass spectrometry (SIFT-MS) and automated sample preparation, determination of benzene, toluene, ethylbenzene, and the xylenes (BTEX) in soil via methanolic extraction is simplified and accelerated. This application note provides an initial validation of the automated SIFT-MS method and demonstrates that the sample throughput achievable with SIFT-MS is at least two-fold higher than gas chromatography (GC).
Enhanced Environmental Monitoring 2: Laboratory Applications
This webinar focuses on the benefits realized by adopting SIFT-MS in environmental testing laboratories, which include reduced sample preparation and increased sample throughput.
Five case studies are presented:
- Soil analysis
- Water headspace analysis
- Formaldehyde analysis using sample bags
- Canister analysis
- Landfill and biogas analysis
Online Demonstration - Part 1: Introducing TD-SIFT-MS for Routine Analysis
Become acquainted with TD-SIFT-MS through the analysis of environmental BTEX (benzene, toluene, ethylbenzene and xylene) from multiple sorbent tubes. This demonstration will address the following; - What makes this approach unique? - What does “real-time” thermal desorption data look like? - How is the automation and processing software operated? - How fast is it?
SIFT-MS Method Validation Webinar
Mark describes how the ICH Q 2 (R1) guidelines can be readily applied to SIFT-MS methods, whether in scenarios where only the analytical technique is changed or for tasks that pose a unique analytical challenge. He presents case studies for two such scenarios: 1) methanolic extraction of BTEX compounds (benzene, toluene, ethylbenzene plus xylenes) from soil, 2) direct analysis of formaldehyde leaching into single-use pharmaceutical devices from polymeric components.
Real-Time Speciation of Ethylbenzene from the Xylenes Using SIFT-MS
Direct mass spectrometry (DMS) techniques struggle to speciate ethylbenzene from the xylene isomers, yet increasingly regulators are imposing different emission and exposure limits for these compounds. This application note describes a significant breakthrough for DMS, because selected ion flow tube mass spectrometry (SIFT-MS) readily achieves direct, real-time speciation of the xylenes from ethylbenzene.
Rapid Analysis of Organochlorine Compounds in Water using Automated SIFT-MS
Combining the power of direct analysis using selected ion flow tube mass spectrometry (SIFTMS) and GERSTEL automation, headspace analysis of chlorinated volatile organic compounds (VOCs) in water is greatly simplified. This application note demonstrates the linearity and and repeatability achievable with automated SIFT-MS. The sample throughput achievable with SIFTMS is at least three-fold higher than traditional purge-and-trap gas chromatography methods.
Syft Tracer: The Next Generation of Volatile Impurities Analysis for Enhanced Workflows
This app note introduces the next generation of SIFT-MS, Syft TracerTM, which launched at Pittcon 2023. It revolutionizes volatile impurities analysis workflows through unparalleled speed, performance stability, and reproducibility. Learn about how this innovation to real-time trace gas detection outpaces chromatography-based methods in the analysis of challenging analytes such as formaldehyde in a PEG excipient.
Recent developments and applications of selected ion flow tube mass spectrometry (SIFT‐MS)
SIFT‐MS is now recognized as the most versatile analytical technique for the identification and quantification of trace gases down to the parts‐per‐trillion by volume, pptv, range. This statement is supported by the wide reach of its applications, from real‐time analysis, obviating sample collection of very humid exhaled breath, to its adoption in industrial scenarios for air quality monitoring. This review touches on the recent extensions to the underpinning ion chemistry kinetics library and the alternative challenge of using nitrogen carrier gas instead of helium.
The Latest Innovation of Real-Time, High-Throughput Volatile Impurities Analysis by SIFT-MS
Join us for this webinar to learn about Syft Tracer, the latest advancement of real-time, trace gas analysis by SIFT-MS which launched at Pittcon 2023. Hear how the recent product innovations unlock analytical bottlenecks and enable faster decisions to be made in critical process steps.
High-Throughput Analysis of Volatile Compounds in Air, Water, and Soil Using SIFT-MS
This study demonstrates high-throughput analysis of BTEX compounds from several matrices (air, water and soil). Detection limits in the single-digit part-per-billion concentration range (by volume) are readily achievable within seconds using SIFT-MS, because sample analysis is achieved without chromatography, pre-concentration, or drying. We also present a calibration approach that enables speciation of ethylbenzene from the xylenes in real time.
Fast, Simple Quantitation of Odors by SIFT-MS
In this on-demand webinar, Michael McGinley, President, St. Croix Sensory, describes how SIFT-MS has advanced their ability to rapidly perform odor analysis. A variety of SIFT-MS-based odor applications correlated with conventional sensory panel assessment are presented. Learn how Syft is Simply. Faster. for the analysis of odor compounds.
Improved MHE-SIFT-MS Workflows - Concentration Independent MHE Calibration
This application note investigates concentration dependence of MHE calibration in sample matrix. Across the full range of analytes investigated in this study, MHE calibration holds for at least one order of magnitude change in sample concentration. For analytes in the C7–C9 range, the MHE calibration applies over two orders of magnitude analyte concentration. These results mean that the MHE workflow can be applied to a wider range of samples in the matrix, further reducing calibration demand.